Description

7-Bromo-6-Methoxy-5-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated azaindole structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo-azaindole moiety into more complex molecular architectures.
• Biochemical Tool Compound Development: Serves as a starting material for creating probes and inhibitors used in biochemical and cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D with custom synthesis and scale-up.

Basic Information

Product Name	7-Bromo-6-Methoxy-5-Azaindole
CAS No.	1190314-42-1
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	7-Bromo-6-methoxy-1H-pyrrolo[3,2-b]pyridine; 6-Methoxy-7-bromo-5-azaindole; 1H-Pyrrolo[3,2-b]pyridine, 7-bromo-6-methoxy-; 7-Bromo-6-methoxy-1H-pyrrolo[3,2-b]pyridine; 7-Br-6-MeO-5-azaindole
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Methoxy-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.