Description

4-Hydroxy-3-Nitro-5-Azaindole is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its unique fused-ring structure, which serves as a critical scaffold in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Development: Intermediate in the research and synthesis of new active ingredients for crop protection.
• Fine Chemical Synthesis: Specialized reagent for constructing complex heterocyclic systems in custom synthesis and contract manufacturing.
• Biochemical Tool Compound: Used in biochemical assays and as a reference standard in analytical method development.

Basic Information

Product Name	4-Hydroxy-3-Nitro-5-Azaindole
CAS No.	1190314-28-3
Molecular Formula	C7H5N3O3
Molecular Weight	179.14 g/mol
Synonyms	3-Nitro-1H-pyrrolo[3,2-b]pyridin-4-ol; 1H-Pyrrolo[3,2-b]pyridin-4-ol, 3-nitro-; 5-Azaindole-4-ol, 3-nitro-; 3-Nitro-4-hydroxy-5-azaindole; 3-Nitro-4-hydroxy-1H-pyrrolo[3,2-b]pyridine; 4-Hydroxy-3-nitro-1H-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Nitro-5-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.