Description

3-Bromo-7-Hydroxy-6-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is valued for its unique molecular scaffold, which serves as a critical building block in modern medicinal chemistry for the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Serves as a core structure for creating selective probes to study specific enzyme functions and biological pathways.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive bromo and hydroxy functional groups.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and scale-up projects under GMP or non-GMP conditions.

Basic Information

Product Name	3-Bromo-7-Hydroxy-6-Azaindole
CAS No.	1190314-15-8
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	7-Hydroxy-3-bromo-1H-pyrrolo[2,3-c]pyridine; 3-Bromo-1H-pyrrolo[2,3-c]pyridin-7-ol; 3-Bromo-7-hydroxy-1H-pyrrolo[2,3-c]pyridine; 6-Azaindole, 3-bromo-7-hydroxy-; 3-Bromo-7-azaindol-6-ol
EINECS	Contact for details

Quality Control

Our 3-Bromo-7-Hydroxy-6-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.