Description

4-Methoxy-3-Nitro-5-Azaindole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development. The compound is supplied with a high level of purity and consistency to meet the stringent demands of modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted small molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Process Chemistry Development: Employed in route scouting and scale-up synthesis for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for novel heterocyclic chemistry and methodology development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and biotech industries.

Basic Information

Product Name	4-Methoxy-3-Nitro-5-Azaindole
CAS No.	1190314-09-0
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	3-Nitro-4-methoxy-1H-pyrrolo[3,2-b]pyridine; 4-Methoxy-3-nitro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 4-methoxy-3-nitro-; 5-Azaindole, 4-methoxy-3-nitro-; 4-Methoxy-3-nitro-5-aza-indole; 3-Nitro-4-methoxy-5-azaindole
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Nitro-5-Azaindole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.