Description

4-Bromo-5-Aza-2-Oxindole is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in scaffold hopping and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Serves as a building block for developing novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Heterocyclic Compound Library Synthesis: An essential component for creating diverse screening libraries in drug discovery programs.

Basic Information

Product Name	4-Bromo-5-Aza-2-Oxindole
CAS No.	1190313-66-6
Molecular Formula	C7H4BrN2O
Molecular Weight	213.03 g/mol
Synonyms	4-Bromo-1H-pyrrolo[3,2-b]pyridin-2(3H)-one; 4-Bromo-5-azaindolin-2-one; 4-Bromo-5-azaoxindole; 4-Bromo-5-aza-2-oxindole; 1H-Pyrrolo[3,2-b]pyridin-2(3H)-one, 4-bromo-; 4-Bromo-3,4-dihydro-1H-pyrrolo[3,2-b]pyridin-2-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Aza-2-Oxindole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.