Description

3-Chloro-4-Iodo-7-Azaindole is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through cross-coupling and functional group transformations. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, particularly kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for targeted therapies.
• Kinase Inhibitor Scaffold: Serves as a core structure or precursor for molecules designed to modulate kinase activity in disease pathways.
• Agrochemical Research: Used in the synthesis of new active ingredients for crop protection products.
• Material Science: Potential building block for organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target identification.

Basic Information

Item	Details
Product Name	3-Chloro-4-Iodo-7-Azaindole
CAS No.	1190313-54-2
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	4-Iodo-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-4-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-4-iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-chloro-4-iodo-; 4-Iodo-3-chloro-7-azaindole; 3-Cl-4-I-7-Azaindole
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.