Description

6-Cyano-4-Fluoro-7-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused azaindole scaffold, which incorporates strategically placed cyano and fluorine substituents, enabling precise molecular modifications. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the design and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the azaindole core's bioisosteric properties.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides, where the fluorine atom can enhance bioavailability and metabolic stability.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Chemical Biology: Employed as a fluorescent probe or tag precursor in bioconjugation and cellular imaging studies.
• Academic & Contract Research: A versatile reagent for methodological development in organic chemistry, particularly in cross-coupling and heterocycle functionalization reactions.

Basic Information

Product Name	6-Cyano-4-Fluoro-7-Azaindole
CAS No.	1190313-36-0
Molecular Formula	C8H4FN3
Molecular Weight	161.14 g/mol
Synonyms	4-Fluoro-7-azaindole-6-carbonitrile; 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-Cyano-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-6-cyano-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 4-fluoro-; 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Cyano-4-Fluoro-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.