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3-Bromo-6-Methoxy-5-Azaindole CAS NO 1190313-25-7


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CAS No.:1190313-25-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-6-Methoxy-5-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This specialized building block is critical for the research and development of novel small-molecule therapeutics, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted cancer treatments and other biologically active molecules.

Application

  • Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potent kinase inhibitors targeting various oncology pathways.
  • Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Biochemical Probe Development: Serves as a precursor for creating labeled compounds or probes used to study enzyme function and cellular signaling mechanisms.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
  • Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and investigating novel heterocyclic chemistry.

Basic Information

Product Name 3-Bromo-6-Methoxy-5-Azaindole
CAS No. 1190313-25-7
Molecular Formula C8H7BrN2O
Molecular Weight 227.06 g/mol
Synonyms 3-Bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine; 6-Methoxy-3-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-6-methoxy-; 3-Bromo-6-methoxy-7-azaindole; 3-Bromo-6-methoxypyrrolo[2,3-b]pyridine
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Quality Control

Every batch of 3-Bromo-6-Methoxy-5-Azaindole is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications developed for pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) providing batch-specific purity, identity, and impurity profile data is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH Q3C guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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