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3-Bromo-6-Methoxy-5-Azaindole CAS NO 1190313-25-7
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CAS No.:1190313-25-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-6-Methoxy-5-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This specialized building block is critical for the research and development of novel small-molecule therapeutics, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted cancer treatments and other biologically active molecules.
Application
- Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potent kinase inhibitors targeting various oncology pathways.
- Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
- Biochemical Probe Development: Serves as a precursor for creating labeled compounds or probes used to study enzyme function and cellular signaling mechanisms.
- Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
- Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and investigating novel heterocyclic chemistry.
Basic Information
| Product Name | 3-Bromo-6-Methoxy-5-Azaindole |
| CAS No. | 1190313-25-7 |
| Molecular Formula | C8H7BrN2O |
| Molecular Weight | 227.06 g/mol |
| Synonyms | 3-Bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine; 6-Methoxy-3-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-6-methoxy-; 3-Bromo-6-methoxy-7-azaindole; 3-Bromo-6-methoxypyrrolo[2,3-b]pyridine |
| EINECS | Contact for details |
Quality Control
Every batch of 3-Bromo-6-Methoxy-5-Azaindole is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications developed for pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) providing batch-specific purity, identity, and impurity profile data is provided with each shipment to support your regulatory and R&D documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 1.0% |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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