Description

6-Methoxy-5-Azaindole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This heterocyclic carboxylic acid derivative serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to synthesize complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors targeting various oncology and inflammatory pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological targets and signaling mechanisms.
• Fine Chemical Synthesis: Serves as a specialized building block for the multi-step synthesis of complex heterocyclic compounds.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	6-Methoxy-5-Azaindole-3-Carboxylic Acid
CAS No.	1190313-17-7
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	6-Methoxy-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid; 6-Methoxy-7-azaindole-3-carboxylic acid; 6-Methoxy-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid; 6-Methoxy-5-aza-indole-3-carboxylic acid; 3-Carboxy-6-methoxy-5-azaindole; 6-Methoxy-5-azaindole-3-carboxylic acid; 6-Methoxy-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid; 1190313-17-7
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and R&D requirements. Our quality commitment ensures material suitable for use in advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.