Description

7-Cyano-4-Azaindole-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in modern organic synthesis. Its unique fused-ring structure, featuring both cyano and carboxylic acid functional groups, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides with novel modes of action.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in the design of biochemical tools and diagnostic agents.
• Academic & R&D: A valuable scaffold for medicinal chemistry programs exploring new heterocyclic drug candidates.

Basic Information

Product Name	7-Cyano-4-Azaindole-3-Carboxylic Acid
CAS No.	1190312-72-1
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	4-Aza-7-cyanoindole-3-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 7-cyano-; 7-Cyano-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 7-Cyano-4-azaindole-3-carboxylate; 3-Carboxy-7-cyano-4-azaindole; 7-CN-4-AI-3-COOH; AZD-1480 Intermediate; Kinase Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 7-Cyano-4-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.