Description

6-Hydroxy-7-Azaindole-4-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is a critical building block in the synthesis of novel, small-molecule drug candidates, particularly for applications in oncology and kinase inhibition. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other biologically active molecules.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Research: Serves as a versatile scaffold for the development of new heterocyclic compounds with potential therapeutic applications.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for investigating novel synthetic methodologies and biochemical pathways.

Basic Information

Product Name	6-Hydroxy-7-Azaindole-4-Carboxylic Acid Methyl Ester
CAS No.	1190312-46-9
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	Methyl 6-hydroxy-1H-pyrrolo[2,3-c]pyridine-4-carboxylate; 6-Hydroxy-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid methyl ester; 4-Carbomethoxy-6-hydroxy-7-azaindole; 6-Hydroxy-7-azaindole-4-carboxylic acid methyl ester; Methyl 6-hydroxy-7-azaindole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-7-Azaindole-4-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.