Description

3-Iodo-7-Methyl-4-Azaindole is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space.
• Agrochemical Synthesis: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-rich indole core and halogen substituent.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form carbon-carbon bonds.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and labeled compounds for biochemical and cellular studies.

Basic Information

Product Name	3-Iodo-7-Methyl-4-Azaindole
CAS No.	1190312-40-3
Molecular Formula	C8H7IN2
Molecular Weight	258.06 g/mol
Synonyms	7-Methyl-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-methyl-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-methyl-4-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-7-methyl-; 7-Methyl-3-iodo-4-azaindole; 3-Iodo-7-methyl-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-7-Methyl-4-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.