Description

3-Chloro-4-Azaindole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for medicinal chemists engaged in the research and development of novel small-molecule therapeutics, particularly kinase inhibitors. It serves as a key building block for synthesizing targeted drug candidates in oncology and other therapeutic areas, offering precise structural control for lead optimization.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead compound generation and structure-activity relationship (SAR) studies for new therapeutic targets.
• Oncology Drug Development: Serves as a core scaffold for developing potent and selective anti-cancer agents.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme function and inhibition mechanisms.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	3-Chloro-4-Azaindole-5-Carboxylic Acid
CAS No.	1190312-13-0
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 3-Chloro-4-aza-indole-5-carboxylic acid; 3-Chloro-4-azaindole-5-carboxylic acid; 5-Carboxy-3-chloro-4-azaindole; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 3-Chloro-7-azaindole-5-carboxylic acid (common numbering variation); 3-Chloro-4-aza-1H-indole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Azaindole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.