Description

3-Iodo-6-Methoxy-7-Azaindole-4-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates halogen, methoxy, and aldehyde functional groups, enabling precise and diverse chemical modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the 7-azaindole core's bioisosteric properties.
• Agrochemical Research: Used in developing new herbicides and fungicides, where the halogenated azaindole structure can confer specific biological activity.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty dyes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological processes.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl systems.
• Medicinal Chemistry SAR Studies: The aldehyde group allows for facile derivatization (e.g., reductive amination, condensation) to explore structure-activity relationships in drug discovery programs.

Basic Information

Product Name	3-Iodo-6-Methoxy-7-Azaindole-4-Carbaldehyde
CAS No.	1190312-11-8
Molecular Formula	C9H7IN2O2
Molecular Weight	302.07 g/mol
Synonyms	4-Formyl-3-iodo-6-methoxy-1H-pyrrolo[2,3-b]pyridine; 6-Methoxy-3-iodo-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde; 3-Iodo-6-methoxy-1H-pyrrolo[2,3-b]pyridine-4-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-4-carboxaldehyde, 3-iodo-6-methoxy-; 3-Iodo-6-methoxy-7-aza-indole-4-carbaldehyde; 3-Iodo-6-methoxy-7-azaindole-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Methoxy-7-Azaindole-4-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.