Description

2-Methyl-5-Trifluoromethyl-4-Azaindole CAS NO 1190311-87-5 is a high-value, fluorinated azaindole derivative, a crucial building block in modern organic synthesis. Its unique structure, featuring both a methyl and a trifluoromethyl group on the azaindole core, makes it an essential intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research and development chemists in the pharmaceutical industry for creating targeted small molecule therapies, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products, leveraging the biological activity of the azaindole scaffold.
• Material Science Precursor: Serves as a building block for organic electronic materials and specialty polymers where fluorinated heterocycles are required.
• Chemical Biology Probe Development: Utilized in creating molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies and the exploration of new synthetic routes involving fluorinated heterocycles.

Basic Information

Product Name	2-Methyl-5-Trifluoromethyl-4-Azaindole
CAS No.	1190311-87-5
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	5-(Trifluoromethyl)-2-methyl-4-azaindole; 2-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 5-Trifluoromethyl-2-methyl-4-azaindole
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-Trifluoromethyl-4-Azaindole is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.