Description

6-Trifluoromethyl-4-Azaindole-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique combination of the 4-azaindole scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly kinase inhibitors and other biologically relevant small molecules.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, especially protein kinase inhibitors.
• Building block for advanced agrochemical research, including the development of new herbicides and fungicides.
• Precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Versatile scaffold for constructing complex heterocyclic libraries in combinatorial chemistry.
• Research chemical for studying enzyme inhibition mechanisms and biological pathways.
• Starting material for the development of fluorescent probes or other diagnostic agents.

Basic Information

Product Name	6-Trifluoromethyl-4-Azaindole-3-Carboxylic Acid
CAS No.	1190311-80-8
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid; 4-Azaindole-3-carboxylic acid, 6-trifluoromethyl-; 6-Trifluoromethyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic Acid; 6-CF3-4-Azaindole-3-Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-4-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.