Description

6-Trifluoromethyl-4-Azaindole-3-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of the electron-withdrawing trifluoromethyl group and the reactive aldehyde moiety on the azaindole scaffold, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by incorporating the trifluoromethyl group to enhance biological activity and metabolic stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: A versatile reagent for methodological development in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	6-Trifluoromethyl-4-Azaindole-3-Carbaldehyde
CAS No.	1190311-65-9
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	1H-Pyrrolo[3,2-b]pyridine-3-carboxaldehyde, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde; 6-(Trifluoromethyl)-4-azaindole-3-carboxaldehyde; 3-Formyl-6-trifluoromethyl-4-azaindole; 6-Trifluoromethyl-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde; 6-Trifluoromethyl-4-aza-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-4-Azaindole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to reliable supply and traceable documentation supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.