Description

5-Cyano-4-Azaindole-3-Carboxylic Acid is a high-value heterocyclic building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery programs for oncology, inflammatory diseases, and central nervous system disorders.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small molecule kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel heterocyclic libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves as a building block in the research and process development stages of Active Pharmaceutical Ingredient (API) manufacturing.
• Biochemical Tool Compound: Utilized in the development of probes and assay reagents for studying enzymatic activity and cellular signaling.

Basic Information

Product Name	5-Cyano-4-Azaindole-3-Carboxylic Acid
CAS No.	1190311-47-7
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	4-Azaindole-3-carboxylic acid, 5-cyano-; 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid, 5-cyano-; 5-Cyano-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid; 5-Cyano-4-azaindole-3-carboxylic acid; 3-Carboxy-5-cyano-4-azaindole; 5-CN-4-AIA-3-COOH
EINECS	Contact for details

Quality Control

Our 5-Cyano-4-Azaindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.