Description

3-Chloro-5-Methoxy-4-Azaindole is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile functionalization points.
• Agrochemical Development: Acts as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Chloro-5-Methoxy-4-Azaindole
CAS No.	1190311-31-9
Molecular Formula	C8H7ClN2O
Molecular Weight	182.61 g/mol
Synonyms	3-Chloro-5-methoxy-1H-pyrrolo[2,3-b]pyridine; 5-Methoxy-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-methoxy-7-azaindole; 3-Chloro-5-methoxy-4-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 3-chloro-5-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methoxy-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.