Description

3-Iodo-4-Azaindole-5-Carboxylic Acid is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its functionalized azaindole core.
• Agrochemical Synthesis: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Material Science Precursor: Potential intermediate for the synthesis of organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	3-Iodo-4-Azaindole-5-Carboxylic Acid
CAS No.	1190311-30-8
Molecular Formula	C8H5IN2O2
Molecular Weight	288.04 g/mol
Synonyms	3-Iodo-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid; 3-Iodo-4-azaindole-5-carboxylic acid; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid, 3-iodo-; 3-Iodo-7-azaindole-5-carboxylic acid; 3-Iodo-1H-1,7-diazaindole-5-carboxylic acid; 5-Carboxy-3-iodo-1H-pyrrolo[3,2-b]pyridine; 3-Iodo-4-aza-indole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Azaindole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistent quality and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.