Description

3-Bromo-7-Cyano-4-Fluoro-6-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromo, cyano, and fluoro substituents on an azaindole core, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel kinase inhibitors, receptor antagonists, and other small-molecule drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Serves as a building block for creating new herbicides, fungicides, and insecticides with potentially enhanced efficacy and selectivity.
• Material Science Precursor: Used in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and advanced functional materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-7-Cyano-4-Fluoro-6-Azaindole
CAS No.	1190311-11-5
Molecular Formula	C8H3BrFN3
Molecular Weight	240.03 g/mol
Synonyms	4-Fluoro-3-bromo-7-cyano-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-3-bromo-1H-pyrrolo[2,3-b]pyridine-7-carbonitrile; 3-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine-7-carbonitrile; 6-Azaindole, 3-bromo-7-cyano-4-fluoro-; 1H-Pyrrolo[2,3-b]pyridine-7-carbonitrile, 3-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-7-Cyano-4-Fluoro-6-Azaindole is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical research and development projects. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC-MS, and NMR. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.