Description

5-Chloro-3-Iodo-7-Methyl-4-Azaindole is a halogenated azaindole derivative, a high-value heterocyclic building block prized for its unique molecular architecture. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile scaffold for creating novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for targeting kinase and other enzyme-related pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological processes and protein function.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization due to its reactive halogen substituents.
• Agrochemical Research: Investigated as a potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	5-Chloro-3-Iodo-7-Methyl-4-Azaindole
CAS No.	1190310-96-3
Molecular Formula	C8H6ClIN2
Molecular Weight	292.50 g/mol
Synonyms	7-Methyl-5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-7-methyl-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-chloro-7-methyl-4-azaindole; 5-Chloro-3-iodo-7-methyl-4-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-3-iodo-7-methyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-7-Methyl-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material integrity for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.