Description

3-Bromo-4-Fluoro-6-azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated azaindole scaffold, which serves as a privileged structure for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel small-molecule drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocycle for bioactivity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study enzyme function and protein-protein interactions.
• Material Science Precursor: Potential building block for organic electronic materials and functional polymers due to its electron-rich indole-like structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	3-Bromo-4-Fluoro-6-azaindole
CAS No.	1190310-81-6
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	3-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-3-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-4-fluoro-6-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-4-fluoro-; 6-Azaindole, 3-bromo-4-fluoro-; 3-Br-4-F-6-AI
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-6-azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.