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3-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Tetrahydrofuran-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Propanamide CAS NO 1190249-32-1
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CAS No.:1190249-32-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Tetrahydrofuran-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Propanamide is a sophisticated heterocyclic compound designed for advanced research and development. This molecule is of significant interest due to its unique structural features, combining indole and thiadiazole pharmacophores, which are key scaffolds in medicinal chemistry. It serves as a critical building block or intermediate for pharmaceutical researchers and agrochemical scientists developing new active ingredients. Its primary value lies in enabling the synthesis of novel compounds targeting a range of biological pathways.
Application
- Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and high-throughput screening libraries to explore new biological activities.
- Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic core.
- Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study specific enzyme or receptor functions.
- Organic Synthesis: A versatile intermediate for academic and industrial chemists developing complex molecules for material science or chemical biology.
Basic Information
| Product Name | 3-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Tetrahydrofuran-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Propanamide |
| CAS No. | 1190249-32-1 |
| Molecular Formula | C₁₈H₁₇BrN₄O₂S |
| Molecular Weight | 433.32 g/mol |
| Synonyms | 3-(6-Bromo-1H-indol-1-yl)-N-[(2E)-5-(oxolan-2-yl)-1,3,4-thiadiazol-2-ylidene]propanamide; Propanamide, 3-(6-bromo-1H-indol-1-yl)-N-[(2E)-5-(tetrahydro-2-furanyl)-1,3,4-thiadiazol-2(3H)-ylidene]-; (2E)-3-(6-Bromo-1H-indol-1-yl)-N-[5-(tetrahydrofuran-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]propanamide; 1190249-32-1; 6-Bromo-1H-indole-1-propanamide derivative; THF-thiadiazole indole propanamide |
| EINECS | Contact for details |
Quality Control
Our 3-(6-Bromo-1H-Indol-1-Yl)-n-[(2E)-5-(Tetrahydrofuran-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Propanamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity. For long-term storage, consider using desiccants and an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 3.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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