Description

2-(Bromoethyl-D4)-4-Nitrophenyl Ether is a deuterated organic compound of significant interest in advanced chemical research and development. This deuterium-labeled analog is specifically designed for applications requiring precise isotopic tracing and mechanistic studies. It serves as a critical building block for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the synthesis of labeled active pharmaceutical ingredients (APIs) and for conducting detailed metabolic and pharmacokinetic studies.

Application

• Deuterated API Synthesis: A key precursor in the development of deuterium-labeled pharmaceutical compounds for improved metabolic stability and pharmacokinetic profiles.
• Metabolic Pathway Tracing: Used as a stable isotopic tracer in mass spectrometry and NMR studies to elucidate drug metabolism and degradation pathways.
• Mechanistic Organic Chemistry Research: Employed in kinetic isotope effect (KIE) studies to investigate reaction mechanisms and transition states.
• Agrochemical Development: Utilized in the research and synthesis of novel, labeled agrochemicals for environmental fate and residue analysis studies.
• Material Science: Serves as a specialty monomer or intermediate in the development of advanced polymers and organic electronic materials requiring specific isotopic properties.
• Analytical Standard Production: Manufactured to high purity for use as an internal standard in quantitative LC-MS and GC-MS analysis, ensuring accurate measurement in complex matrices.

Basic Information

Product Name	2-(Bromoethyl-D4)-4-Nitrophenyl Ether
CAS No.	1190017-10-7
Molecular Formula	C8H4D4BrNO3
Molecular Weight	247.08 g/mol (for deuterated form)
Synonyms	1-Bromo-2-(4-nitrophenoxy)ethane-d4; 4-Nitrophenyl 2-bromoethyl-d4 ether; (2-Bromoethyl-d4)-4-nitrophenyl ether; 2-Bromoethyl-d4 4-nitrophenyl ether; p-Nitrophenyl 2-bromoethyl-d4 ether; Deuterated 2-Bromoethyl 4-Nitrophenyl Ether; [D4]-2-Bromoethyl 4-nitrophenyl ether; 4-Nitrophenoxyethyl-d4 bromide
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality management systems to ensure isotopic and chemical purity for sensitive research applications. Each batch undergoes comprehensive analysis including NMR (¹H, ²H, ¹³C) for isotopic enrichment verification and structural confirmation, and HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing isotopic purity (atom % D), chemical assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by ²H NMR)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.