Description

1-(Piperidin-4-Ylmethyl)-3-(Thiazol-2-Yl)Urea 2Hcl is a high-purity, small-molecule chemical building block featuring a urea core linked to piperidine and thiazole heterocycles. This compound is of significant value in pharmaceutical research and development, particularly as a key intermediate for synthesizing novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for hit-to-lead optimization and the creation of targeted molecular libraries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential kinase inhibitors, protease inhibitors, and other enzyme-targeted small molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study specific biological pathways and protein functions.
• Agrochemical Development: Investigated as an intermediate in the research of new crop protection agents and herbicides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	1-(Piperidin-4-Ylmethyl)-3-(Thiazol-2-Yl)Urea 2Hcl
CAS No.	1190016-35-3
Molecular Formula	C11H17Cl2N4OS
Molecular Weight	324.25 g/mol
Synonyms	1-[(Piperidin-4-yl)methyl]-3-(1,3-thiazol-2-yl)urea dihydrochloride; 1-(Piperidin-4-ylmethyl)-3-thiazol-2-ylurea dihydrochloride; Urea, N-[(4-piperidinyl)methyl]-N'-(2-thiazolyl)-, dihydrochloride; 1-(4-Piperidylmethyl)-3-(2-thiazolyl)urea dihydrochloride; 1190016-35-3; UNII-9G8G7J5T4F; 9G8G7J5T4F
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-Ylmethyl)-3-(Thiazol-2-Yl)Urea 2Hcl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.