Description

1-Methyl-5-(Piperidin-4-Yloxy)-1H-Indazole Hcl CAS NO 1190012-49-7 is a high-purity, advanced pharmaceutical intermediate belonging to the indazole chemical class. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Biochemical Research: Used as a reference standard or a starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Organic Synthesis: Employed as a specialized reagent for constructing complex heterocyclic frameworks in academic and industrial laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Methyl-5-(Piperidin-4-Yloxy)-1H-Indazole Hcl
CAS No.	1190012-49-7
Molecular Formula	C14H19N3O·HCl
Molecular Weight	281.78 g/mol
Synonyms	1-Methyl-5-(4-piperidyloxy)-1H-indazole hydrochloride; 5-(Piperidin-4-yloxy)-1-methyl-1H-indazole hydrochloride; 1-Methyl-5-(piperidin-4-yloxy)-1H-indazole hydrochloride; 1-Methyl-5-(4-piperidinoloxy)indazole HCl; 1190012-49-7; UNII-7D8Q8QZ1V6
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-(Piperidin-4-Yloxy)-1H-Indazole Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.