Description

3-Pyridylacetic Acid-D6 is a deuterated analog of 3-pyridylacetic acid, where six hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry analyses, particularly in pharmacokinetic and metabolic studies. It is a critical material for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise measurement of the parent compound in complex biological matrices.

Application

• Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of 3-pyridylacetic acid.
• Critical for drug metabolism and pharmacokinetics (DMPK) studies in pharmaceutical R&D to track absorption, distribution, metabolism, and excretion (ADME).
• Enables accurate bioanalysis in clinical and preclinical trials for drugs where 3-pyridylacetic acid is a metabolite or active pharmaceutical ingredient (API).
• Supports forensic and toxicological analysis for the precise detection and quantification of target analytes.
• Facilitates environmental fate studies of related chemical compounds in agrochemical research.
• Employed in the development and validation of highly sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).

Basic Information

Product Name	3-Pyridylacetic Acid-D6
CAS No.	1190005-72-1
Molecular Formula	C7D6HNO2
Molecular Weight	~143.17 g/mol
Synonyms	3-Pyridylacetic-2,2-d2 acid-d4; (3-Pyridyl)-d5-acetic-d acid; 2-(Pyridin-3-yl)acetic-2,2-d2 acid-d4; 3-Pyridineacetic-d6 acid; Deuteronated 3-Pyridylacetic Acid; 3-Pyridyl-D5-acetic-D acid; 3-Pyridylacetic Acid (Ring-D5, Acetic-D); 3-Pyridylacetic Acid-d6 (Hexadeuterated)
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridylacetic Acid-D6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, typically ≥98% (chemical purity) and ≥99% atom D, to meet the exacting demands of analytical reference standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic purity, and identification by spectroscopic methods (NMR, IR). Our quality commitment aligns with the standards expected for materials used in GLP/GMP-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and deuteration pattern
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % D (by MS)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.