Description

3-(tert-Butyl-D9)-5-[7-(Hydroxyethyl)-2-Benzofuranyl]-2-Oxazolidinone (Mixture Of Diastereomers) is a deuterated isotopologue of a benzofuran-oxazolidinone derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its primary value lies in enabling metabolic and pharmacokinetic studies through the use of stable isotope labeling, which is essential for the development of new therapeutic agents. This compound is particularly vital for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on novel drug discovery, especially for compounds targeting complex biological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic profiles.
• Metabolic Studies: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification and metabolite identification.
• Drug Discovery Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Isotope Effect Investigation: Facilitates the study of kinetic isotope effects (KIE) to understand reaction mechanisms in biological systems.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for analytical method development and validation in regulatory submissions.
• Preclinical Development: Used in the formulation of radiolabeled or isotopically labeled compounds for absorption, distribution, metabolism, and excretion (ADME) studies.

Basic Information

Item	Details
Product Name	3-(tert-Butyl-D9)-5-[7-(Hydroxyethyl)-2-Benzofuranyl]-2-Oxazolidinone (Mixture Of Diastereomers)
CAS No.	1189998-94-4
Molecular Formula	C₁₇H₁₃D₉NO₄
Molecular Weight	Contact for details
Synonyms	3-(tert-Butyl-d9)-5-(7-(2-hydroxyethyl)benzofuran-2-yl)oxazolidin-2-one; Deuterated Benzofuran-Oxazolidinone Intermediate; (tert-Butyl-d9)-Benzofuranyl Oxazolidinone; 5-[7-(2-Hydroxyethyl)-1-benzofuran-2-yl]-3-(1,1-dimethylethyl-d9)-2-oxazolidinone; Isotopically Labeled Oxazolidinone Derivative; Deuterated Drug Intermediate 1189998-94-4; 3-(tert-Butyl-D9)-5-(7-(Hydroxyethyl)benzofuranyl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our 3-(tert-Butyl-D9)-5-[7-(Hydroxyethyl)-2-Benzofuranyl]-2-Oxazolidinone (Mixture Of Diastereomers) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing results from HPLC, NMR, and LC-MS are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Isotopic Enrichment (LC-MS)	≥ 98 atom % D
Diastereomeric Ratio	Specified per batch
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.