Description

n-[2-[4-[[4-(Hydroxymethyl)Cyclohexyl]Carbamoylsulfamoyl]Phenyl]Ethyl]-3-Methyl-5-Oxo-4-(1,1,2,2,2-Pentadeuterioethyl)-2H-Pyrrole-1-Carboxamide CAS NO 1189980-46-8 is a deuterated pyrrole derivative, a high-value synthetic intermediate designed for advanced research and development. This compound is critical for applications requiring isotopic labeling, offering enhanced metabolic stability and traceability in analytical studies. It is primarily utilized by pharmaceutical and agrochemical R&D teams for drug discovery, metabolite identification, and mechanistic studies.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) for improved pharmacokinetic profiles.
• Metabolite Tracing: Used in mass spectrometry and NMR studies to track and identify drug metabolites in biological systems.
• Agrochemical Development: Serves as a key building block in the research of new, isotopically-labeled crop protection agents.
• Chemical Biology Probes: Enables the creation of molecular probes for studying enzyme mechanisms and protein interactions.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale synthesis of deuterated compounds.
• Analytical Reference Standards: Provides a high-purity, isotopically-labeled standard for quantitative and qualitative analysis in regulatory and quality control laboratories.

Basic Information

Product Name	n-[2-[4-[[4-(Hydroxymethyl)Cyclohexyl]Carbamoylsulfamoyl]Phenyl]Ethyl]-3-Methyl-5-Oxo-4-(1,1,2,2,2-Pentadeuterioethyl)-2H-Pyrrole-1-Carboxamide
CAS No.	1189980-46-8
Molecular Formula	C24H31D5N4O5S
Molecular Weight	503.66 g/mol (deuterated form)
Synonyms	Deuterated Pyrrole-1-Carboxamide Derivative; 4-(Pentadeuterioethyl)-3-methyl-5-oxo-N-[2-[4-[[(4-(hydroxymethyl)cyclohexyl)carbamoyl]sulfamoyl]phenyl]ethyl]-2H-pyrrole-1-carboxamide; 1189980-46-8; Deuterated Sulfonylurea Pyrrole Intermediate; [D5]-Labeled Cyclohexylcarbamoylsulfamoyl Phenyl Ethyl Pyrrole Carboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, isotopic enrichment (D-content), and structural confirmation (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can adhere to cGMP guidelines for advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Enrichment (D-content)	≥ 95 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.