Description

2,2,3,3,5,5,6,6-Octadeuterio-1-[3-(Trifluoromethyl)Phenyl]Piperazine:Hydrochloride is a high-purity, deuterium-labeled chemical building block essential for advanced research and development. Its core value lies in providing a stable, isotopically labeled internal standard for precise quantitative analysis in complex matrices. This compound is critically needed by pharmaceutical, agrochemical, and analytical chemistry laboratories engaged in drug metabolism and pharmacokinetics (DMPK) studies, environmental fate analysis, and forensic toxicology.

Application

• Primary use as a stable isotope-labeled internal standard for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) quantification.
• Critical component in pharmaceutical research for tracing the metabolism of piperazine-based drug candidates and their trifluoromethylphenyl analogs.
• Enables accurate bioanalytical method development and validation in clinical and pre-clinical studies to meet regulatory requirements.
• Used in environmental science for detecting and quantifying trace levels of related chemical pollutants.
• Facilitates forensic analysis by providing a definitive reference for identifying specific substances in toxicological screenings.
• Serves as a specialized precursor or intermediate in the synthesis of deuterated novel chemical entities for research purposes.

Basic Information

Product Name	2,2,3,3,5,5,6,6-Octadeuterio-1-[3-(Trifluoromethyl)Phenyl]Piperazine:Hydrochloride
CAS No.	1189975-78-7
Molecular Formula	C11H5D8F3N2·HCl
Molecular Weight	284.75 g/mol (approx.)
Synonyms	1-(3-Trifluoromethylphenyl)piperazine-d8 hydrochloride; 3-(Trifluoromethyl)phenylpiperazine-d8 HCl; 3-TFMPP-d8 hydrochloride; Deuterated 1-(3-Trifluoromethylphenyl)piperazine hydrochloride; Octadeuterio-1-(3-(trifluoromethyl)phenyl)piperazine hydrochloride; 1-(m-Trifluoromethylphenyl)piperazine-d8 hydrochloride; 3-CF3-PP-d8 HCl
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is produced and tested to meet the stringent requirements of research and analytical applications. We guarantee high chemical and isotopic purity, with comprehensive testing including assay by NMR or HPLC, deuterium enrichment by MS, and control of related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for identity, purity, and isotopic content to ensure traceability and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.