Description

8-Hydroxy-3,4-Dihydro-1H-Isoquinoline-2-Carboximidamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoquinoline-based molecular scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing new therapeutic agents and specialty compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides due to its bioactive heterocyclic structure.
• Biochemical Reagent: Employed as a standard or reagent in biochemical assays and diagnostic research.
• Fine Chemical Synthesis: Acts as a building block for creating complex molecules used in material science and specialty chemistry applications.

Basic Information

Product Name	8-Hydroxy-3,4-Dihydro-1H-Isoquinoline-2-Carboximidamide
CAS No.	1189975-64-1
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	8-Hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboximidamide; 1H-Isoquinoline-2-carboximidamide, 3,4-dihydro-8-hydroxy-; 8-Hydroxy-3,4-dihydro-1H-isoquinoline-2-carboximidamide; 2-Carbamimidoyl-8-hydroxy-1,2,3,4-tetrahydroisoquinoline; 8-Hydroxytetrahydroisoquinoline-2-carboximidamide
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-3,4-Dihydro-1H-Isoquinoline-2-Carboximidamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.