Description

3,3-Diphenyl-n-(Trideuteriomethyl)Propanamide is a deuterated organic compound of significant interest in advanced chemical research and development. This deuterium-labeled analog serves as a critical building block and internal standard, enabling precise analytical and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions specializing in isotope chemistry and tracer methodologies.

Application

• Pharmaceutical Research: Acts as a deuterium-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods like LC-MS/MS.
• Metabolic Studies: Used as a stable isotope tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of lead compounds in drug discovery.
• Mechanistic Probes: Employed in chemical and biochemical reaction studies to elucidate mechanisms via kinetic isotope effect (KIE) experiments.
• Reference Material: Serves as a high-purity certified reference material (CRM) for calibrating analytical instruments and validating methods in quality control laboratories.
• Agrochemical Development: Utilized in the synthesis and study of novel, labeled agrochemicals to track environmental fate and degradation pathways.
• Academic Synthesis: A valuable intermediate for university research in synthetic organic chemistry, particularly in methodologies involving isotopic labeling.

Basic Information

Product Name	3,3-Diphenyl-n-(Trideuteriomethyl)Propanamide
CAS No.	1189967-22-3
Molecular Formula	C₁₆H₁₅D₃NO
Molecular Weight	242.33 g/mol
Synonyms	N-(Trideuteriomethyl)-3,3-diphenylpropanamide; 3,3-Diphenyl-N-(trideuteromethyl)propanamide; 3,3-Diphenylpropanamide-N-CD3; Deuterated 3,3-Diphenyl-N-methylpropanamide; [D3]-3,3-Diphenyl-N-methylpropanamide; Propanamide, N-(trideuteriomethyl)-3,3-diphenyl-; 1189967-22-3; (3,3-Diphenylpropionyl)methyl-d3-amine
EINECS	Contact for details

Quality Control

Our 3,3-Diphenyl-n-(Trideuteriomethyl)Propanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, and Deuterium) for structural confirmation and isotopic enrichment, and HPLC for chemical and isotopic purity assessment. Certificates of Analysis (COA) detailing all specifications, including deuterium incorporation, are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.