Description

Alpidem-D14 is a deuterated internal standard of the anxiolytic agent Alpidem, specifically designed for use in quantitative mass spectrometry. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of analytical results in pharmacokinetic and metabolic studies. It is a critical tool for researchers and quality control laboratories in the pharmaceutical and contract research organization (CRO) sectors who require precise quantification of Alpidem and its metabolites.

Application

• Primary use as an internal standard for LC-MS/MS and GC-MS analysis in bioanalytical method development and validation.
• Quantification of Alpidem in pharmacokinetic studies, including plasma, serum, and urine sample analysis.
• Metabolite profiling and drug metabolism studies to understand the biotransformation pathways of Alpidem.
• Supporting forensic and clinical toxicology investigations requiring accurate drug level measurement.
• Quality control and assurance in pharmaceutical manufacturing for batch consistency testing.
• Use in environmental fate studies tracking pharmaceutical residues, though this is a secondary application.

Basic Information

Product Name	Alpidem-D14
CAS No.	1189962-23-9
Molecular Formula	C21H15D14N3O
Molecular Weight	~369.55 g/mol
Synonyms	Alpidem-d14; 6-Chloro-2-(4-chlorophenyl)-N,N-dimethyl-2H-imidazo[1,2-a][1,4]benzodiazepine-2-acetamide-d14; Deuterated Alpidem; Alpidem (phenyl-d5, imidazole-d4, acetamide-d5); LS. 65011-d14; AN 561-d14; Internal Standard for Alpidem
EINECS	Contact for details

Quality Control

Every batch of Alpidem-D14 is manufactured and analyzed under strict quality protocols to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), isotopic purity (by MS), and chemical identity confirmation. Our quality system is designed to support GMP/GLP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.