Description

2-n-Butyl-D3-1,3-Diazaspiro[4.4]Non-1-En-4-One is a deuterium-labeled spirocyclic compound, a valuable isotopically labeled building block for advanced chemical synthesis. Its primary value lies in its role as a stable isotope-labeled internal standard, which is critical for ensuring the accuracy and reliability of quantitative analytical methods. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing and validating analytical methods for pharmacokinetic studies, metabolic profiling, and quality control of complex organic molecules.

Application

• As a deuterated internal standard for the precise quantification of its non-labeled counterpart in complex matrices using LC-MS/MS and GC-MS.
• In pharmaceutical research for drug metabolism and pharmacokinetics (DMPK) studies, enabling accurate tracking of drug candidates.
• For the synthesis of isotope-labeled analogs of bioactive molecules in medicinal chemistry programs.
• In agrochemical analysis as a reference standard for the detection and measurement of pesticides or their metabolites.
• As a specialized reagent in organic synthesis for introducing a deuterated spirocyclic moiety into target molecules.
• Supporting forensic and environmental analysis where high-precision isotope dilution techniques are required.

Basic Information

Product Name	2-n-Butyl-D3-1,3-Diazaspiro[4.4]Non-1-En-4-One
CAS No.	1189960-20-0
Molecular Formula	C11H15D3N2O
Molecular Weight	197.28 g/mol
Synonyms	2-(Butyl-d3)-1,3-diazaspiro[4.4]non-1-en-4-one; Deuterated 2-n-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one; 2-(n-Butyl-d3)-1,3-diazaspiro[4.4]non-1-en-4-one; 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-(butyl-d3)-; 2-(Butyl-1,1,1-d3)-1,3-diazaspiro[4.4]non-1-en-4-one; Spirocyclic deuterated lactam
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS. Certificates of Analysis (COA) are provided, detailing parameters such as chemical purity, isotopic enrichment (D-content), and identity confirmation. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.