Description

Narcobarbital-D7 CAS NO 1189950-65-9 is a high-purity, deuterium-labeled internal standard critical for ensuring analytical accuracy and reliability in quantitative mass spectrometry. This stable isotope-labeled compound is essential for researchers and quality control laboratories requiring precise measurement and validation of the parent compound, Narcobarbital. It is primarily used in forensic toxicology, pharmaceutical research, and clinical diagnostics for method development and compliance testing.

Application

• Quantitative Mass Spectrometry: Serves as a deuterated internal standard for the accurate quantification of Narcobarbital in complex biological matrices via LC-MS/MS and GC-MS.
• Forensic and Clinical Toxicology: Enables precise measurement of barbiturate levels in blood, urine, and tissue samples for legal and medical investigations.
• Pharmaceutical R&D: Used in pharmacokinetic and metabolic stability studies to track the absorption, distribution, metabolism, and excretion (ADME) of the active pharmaceutical ingredient.
• Method Development and Validation: Critical for developing, calibrating, and validating robust analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Quality Control & Assurance: Employed in pharmaceutical manufacturing QC labs to monitor for impurities and ensure batch-to-batch consistency.
• Reference Material: Acts as a certified reference material (CRM) for instrument calibration and proficiency testing in accredited laboratories.

Basic Information

Product Name	Narcobarbital-D7
CAS No.	1189950-65-9
Molecular Formula	C12H11D7N2O3
Molecular Weight	245.31 g/mol
Synonyms	5-Ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione-d7; Barbital-d7; Veronal-d7; Diethylmalonylurea-d7; 5,5-Diethylbarbituric Acid-d7; Barbitone-d7; Dormonal-d7; Medinal-d7
EINECS	Contact for details

Quality Control

Our Narcobarbital-D7 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (by MS), and residual solvent content. We support compliance with cGMP and ISO 17034 standards for reference materials. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98.0 atom % D
Chemical Purity (Titration)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.