Description

5-(4-Chlorophenyl)-6-(2,2,2-Trideuterioethyl)Pyrimidine-2,4-Diamine is a deuterated pyrimidine derivative, a high-value building block designed for advanced research and development. This compound is critical for applications requiring isotopic labeling, offering enhanced metabolic stability and traceability in pharmacokinetic and mechanistic studies. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as academic researchers focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key deuterated synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and antiviral agents.
• Metabolic Studies: Used as an internal standard or a labeled precursor in mass spectrometry-based assays for drug metabolism and pharmacokinetics (DMPK) research.
• Mechanistic Probe: Enables the study of metabolic pathways and reaction mechanisms through deuterium isotope effects in chemical and biological systems.
• Agrochemical Research: Acts as a building block for developing novel, isotopically labeled pesticides or herbicides with improved environmental and metabolic profiles.
• Material Science: Potential use in the development of organic electronic materials and liquid crystals where specific deuterium substitution is required.

Basic Information

Product Name	5-(4-Chlorophenyl)-6-(2,2,2-Trideuterioethyl)Pyrimidine-2,4-Diamine
CAS No.	1189936-99-9
Molecular Formula	C12H10D3ClN4
Molecular Weight	251.73 g/mol
Synonyms	5-(4-Chlorophenyl)-6-(2,2,2-trideuteroethyl)pyrimidine-2,4-diamine; 6-(2,2,2-Trideuterioethyl)-5-(4-chlorophenyl)pyrimidine-2,4-diamine; 5-(p-Chlorophenyl)-6-(trideuteroethyl)pyrimidine-2,4-diamine; Deuterated Pyrimidine Diamine; [D3]-5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-6-(2,2,2-Trideuterioethyl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and isotopic enrichment analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain isotopic purity and compound integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.