Description

1-(3-Chlorophenyl)Piperazine-D8 is a deuterated analog of 1-(3-Chlorophenyl)piperazine, a compound of significant interest in pharmaceutical and biochemical research. This high-purity, isotopically labeled standard is essential for ensuring accuracy and reliability in quantitative analytical methods. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors for applications requiring precise internal standards.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical, non-interfering reference compound in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of its non-deuterated counterpart and related metabolites.
• Pharmacokinetic and Metabolite Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Drug Metabolism Research: Used to study metabolic pathways and identify potential bioactive or toxic metabolites of pharmaceutical compounds.
• Forensic and Clinical Toxicology: Provides a reliable standard for the detection and quantification of specific substances in complex biological matrices.
• Method Development and Validation: Essential for developing robust, sensitive, and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH).
• Isotope Dilution Analysis: Fundamental to high-precision quantitative analysis techniques that correct for sample preparation and instrument variability.

Basic Information

Product Name	1-(3-Chlorophenyl)Piperazine-D8
CAS No.	1189923-43-0
Molecular Formula	C10H5D8ClN2
Molecular Weight	213.75 g/mol (approx.)
Synonyms	1-(3-Chlorophenyl)piperazine-d8; 3-Chlorophenylpiperazine-d8; m-Chlorophenylpiperazine-d8; 1-(m-Chlorophenyl)piperazine-d8; mCPP-d8; Deuterated mCPP; [D8]-1-(3-Chlorophenyl)piperazine; 1-(3-Chlorophenyl)piperazine (octadeuterated)
EINECS	Contact for details

Quality Control

Our 1-(3-Chlorophenyl)Piperazine-D8 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical data is provided with every shipment to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.