Description

Pyridoxine-[D3] HCl (Vitamin B6-[D3]) is a high-purity, deuterium-labeled isotopologue of pyridoxine hydrochloride, a critical form of Vitamin B6. This stable isotope-labeled compound is essential for advanced analytical and research applications where precise metabolic tracing is required. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and manufacturers of diagnostic assays and reference standards.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical quantitative reference in LC-MS/MS and GC-MS analysis for accurate measurement of Vitamin B6 levels in complex biological matrices.
• Pharmacokinetic & Metabolic Studies: Enables precise tracking of Vitamin B6 absorption, distribution, metabolism, and excretion (ADME) in drug development and nutritional research.
• Clinical Diagnostics: Used in the development and calibration of high-sensitivity diagnostic kits for assessing Vitamin B6 status and related metabolic disorders.
• Stable Isotope Labeling in Biochemistry: A vital tool for probing enzymatic mechanisms and metabolic pathways involving pyridoxal phosphate-dependent enzymes.
• Manufacturing Reference Standards: Employed in the production of certified reference materials (CRMs) for quality control in pharmaceutical and nutraceutical industries.
• Nutritional Research: Facilitates advanced studies on Vitamin B6 bioavailability, fortification, and its role in human health.

Basic Information

Product Name	Pyridoxine-[D3] HCl (Vitamin B6-[D3])
CAS No.	1189921-12-7
Molecular Formula	C8H8D3ClNO3
Molecular Weight	208.66 g/mol
Synonyms	Vitamin B6-d3 hydrochloride; Pyridoxine-d3 HCl; 5-Deuteroxy-4-(deuteroxymethyl)-2-methylpyridin-3-ol-d hydrochloride; 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine-d3 hydrochloride; Pyridoxol-d3 hydrochloride; Pyridoxine (D3) hydrochloride; Deuterated Pyridoxine HCl; Stable Isotope Labeled Vitamin B6 HCl
EINECS	Contact for details

Quality Control

Our Pyridoxine-[D3] HCl is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry standards for stable isotope-labeled compounds, ensuring reliable performance and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Isotopic Enrichment	≥98 atom % D
Chemical Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.