Description

2-Butyl-D3-4-Chloro-5-Benzyloxymethyl-1H-Imidazole is a high-purity, deuterated imidazole derivative of significant interest in advanced chemical synthesis and pharmaceutical research. This compound is valued for its role as a stable isotope-labeled intermediate, enabling precise metabolic and pharmacokinetic studies. It is primarily utilized by research institutions and pharmaceutical developers working on novel therapeutic agents, particularly in the areas of enzyme inhibition and drug discovery.

Application

• As a deuterated building block in the synthesis of novel pharmaceutical candidates for metabolic studies.
• Use as a key intermediate in the research and development of enzyme inhibitors and receptor modulators.
• In isotope labeling programs to create internal standards for accurate mass spectrometry (LC-MS/MS) analysis.
• For preclinical research in drug discovery pipelines, aiding in the investigation of drug metabolism and pharmacokinetics (DMPK).
• As a specialty chemical in advanced organic synthesis for academic and industrial R&D laboratories.

Basic Information

Product Name	2-Butyl-D3-4-Chloro-5-Benzyloxymethyl-1H-Imidazole
CAS No.	1189919-69-4
Molecular Formula	C15H17D3ClN2O
Molecular Weight	282.81 g/mol (for monoisotopic mass)
Synonyms	2-(Butyl-d3)-4-chloro-5-(benzyloxymethyl)-1H-imidazole; 4-Chloro-5-(benzyloxymethyl)-2-(butyl-d3)-1H-imidazole; 2-Butyl-d3-4-chloro-5-(phenylmethoxy)methyl-1H-imidazole; Deuterated 2-Butyl-4-chloro-5-benzyloxymethylimidazole; CAS 1189919-69-4
EINECS	Contact for details

Quality Control

Our 2-Butyl-D3-4-Chloro-5-Benzyloxymethyl-1H-Imidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (D-content), and impurity profile. We adhere to cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.