Description

N,1-Dimethyl-4-Nitro-5-Imidazolecarboxamide-D3 is a deuterated derivative of a key imidazole-based chemical intermediate. This compound is significant for its role as a stable isotope-labeled standard in advanced analytical and research applications, ensuring precise quantification and reliable results. It is primarily required by pharmaceutical research and development laboratories, analytical service providers, and manufacturers of high-purity reference materials.

Application

• As an internal standard in quantitative mass spectrometry (LC-MS/MS, GC-MS) for pharmacokinetic and bioanalytical studies.
• Use in deuterium-labeled pharmaceutical research and development for metabolic pathway tracing.
• Critical for method development and validation in regulatory-compliant analytical laboratories.
• Production of certified reference materials (CRMs) for quality control and assurance programs.
• Application in isotope dilution analysis to achieve high accuracy in complex sample matrices.
• Research tool in drug discovery for investigating the metabolism of imidazole-containing drug candidates.

Basic Information

Product Name	N,1-Dimethyl-4-Nitro-5-Imidazolecarboxamide-D3
CAS No.	1189907-32-1
Molecular Formula	C7H6D3N5O3
Molecular Weight	212.19 g/mol
Synonyms	4-Nitro-1H-imidazole-5-carboxamide, N,1-dimethyl-, D3-labeled; 1-Methyl-4-nitro-5-(N-methylcarbamoyl)imidazole-D3; D3-Labeled Dacarbazine Impurity/Intermediate; Deuterated N,1-Dimethyl-4-nitro-1H-imidazole-5-carboxamide; (1-Methyl-4-nitro-1H-imidazol-5-yl)(methyl-D3)carbamic acid amide; DTIC-D3; Isotopically Labeled Imidazolecarboxamide
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced and tested under stringent conditions to ensure exceptional isotopic purity and chemical integrity, meeting the exacting requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity by HPLC, and identity confirmation. We adhere to ISO-guided quality management principles, and specifications can be aligned with client-specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.