Description

Oxolinic Acid-D5 is a deuterium-labeled analog of the quinolone antibiotic oxolinic acid, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and food safety sectors who require precise measurement of oxolinic acid residues or metabolites.

Application

• Internal Standard for LC-MS/MS: Primary application as a deuterated internal standard for the precise quantification of oxolinic acid in complex biological and environmental matrices.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic and pharmacodynamic studies to track the absorption, distribution, metabolism, and excretion of oxolinic acid.
• Veterinary Drug Residue Analysis: Critical for testing meat, fish, and other animal products for compliance with maximum residue limits (MRLs) of oxolinic acid.
• Environmental Monitoring: Employed in the analysis of water and soil samples to detect and quantify antibiotic pollution from agricultural or aquaculture sources.
• Method Development & Validation: Serves as a key component in developing, optimizing, and validating new analytical methods for quinolone antibiotics.
• Quality Control & Assurance: Used in-house by manufacturers of pharmaceuticals or analytical standards to ensure batch consistency and accuracy of their own products.

Basic Information

Product Name	Oxolinic Acid-D5
CAS No.	1189890-98-9
Molecular Formula	C13H6D5NO5
Molecular Weight	268.25 g/mol
Synonyms	5-Ethyl-2,8-dioxo-1,2,3,8-tetrahydro-5H-oxazolo[3,2-a]quinoline-7-carboxylic-2,3,4,5,6-D5 acid; Deuterated Oxolinic Acid; Oxolinic Acid (phenyl-D5); 1-Ethyl-6,7-dihydro-4-hydroxy-1,8-naphthyridine-3-carboxylic-2,3,4,5,6-D5 acid; 5-Ethyl-5,8-dihydro-8-oxo[1,3]dioxolo[4,5-g]quinoline-7-carboxylic-2,3,4,5,6-D5 acid; Oxolinic Acid-d5 (Internal Standard)
EINECS	Contact for details

Quality Control

Our Oxolinic Acid-D5 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR and HPLC-MS, to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D5 ≥ 98%), chemical purity (typically ≥ 95% by HPLC), and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Isotopic Purity (D5)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.