Description

1,1,2,2-Tetradeuterio-n-Methyl-2-(4-Nitrophenoxy)-n-[2-(4-Nitrophenyl)Ethyl]Ethanamine is a deuterated derivative of a key chemical intermediate, offering enhanced stability and unique properties for advanced research and development. This compound is critical for applications requiring precise isotopic labeling, particularly in mechanistic studies and analytical method development. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and contract research organizations (CROs) specializing in isotope chemistry and metabolic pathway analysis.

Application

• Pharmaceutical Research: As a deuterium-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods (LC-MS/MS).
• Metabolic Studies: For tracing metabolic pathways and identifying metabolites in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, and Excretion) research.
• Mechanistic Chemistry: Employed in kinetic isotope effect (KIE) studies to investigate reaction mechanisms and transition states in organic synthesis.
• Agrochemical Development: Used in the development and validation of analytical methods for pesticide residue analysis and environmental fate studies.
• Isotope Chemistry: Serves as a specialized building block for the synthesis of more complex deuterated molecules in medicinal chemistry.
• Quality Control & Reference Standards: Acts as a certified reference material (CRM) for ensuring the accuracy and precision of analytical instrumentation in quality control laboratories.

Basic Information

Product Name	1,1,2,2-Tetradeuterio-n-Methyl-2-(4-Nitrophenoxy)-n-[2-(4-Nitrophenyl)Ethyl]Ethanamine
CAS No.	1189869-42-8
Molecular Formula	C17H15D4N3O4
Molecular Weight	329.36 g/mol
Synonyms	N-Methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethanamine-d4; Deuterated N-Methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethanamine; N-Methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethan-1,1,2,2-d4-amine; 1,1,2,2-Tetradeuterio-N-methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethanamine; D4-Labeled N-Methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethanamine; [D4]-N-Methyl-2-(4-nitrophenoxy)-N-[2-(4-nitrophenyl)ethyl]ethanamine
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR (¹H, ²H) and high-resolution mass spectrometry (HRMS). A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and analytical data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (²H NMR)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.