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1,3-Dichloro-2-(Methoxymethoxy)Propane-D5 CAS NO 1189863-31-7


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CAS No.:1189863-31-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3-Dichloro-2-(Methoxymethoxy)Propane-D5 is a deuterated analog of a versatile chloromethyl ether building block, specifically designed for advanced research and development. This isotopically labeled compound is critical for mechanistic studies, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry. It is primarily sought after by pharmaceutical researchers, agrochemical developers, and analytical laboratories engaged in the synthesis of complex molecules where precise tracking and quantification are essential.

Application

  • Pharmaceutical Research: As a deuterium-labeled intermediate for synthesizing isotopically labeled drug candidates for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
  • Analytical Chemistry: Use as a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart or related metabolites via LC-MS or GC-MS.
  • Mechanistic Studies: Employed in reaction mechanism elucidation and isotope effect investigations in organic synthesis.
  • Agrochemical Development: As a building block for creating labeled analogs of pesticides or herbicides for environmental fate and metabolic studies.
  • Material Science: Potential use in the synthesis of specialized polymers or coatings where deuterium incorporation modifies physical properties.

Basic Information

Product Name 1,3-Dichloro-2-(Methoxymethoxy)Propane-D5
CAS No. 1189863-31-7
Molecular Formula C5H5D5Cl2O2
Molecular Weight 188.07 g/mol (deuterated form)
Synonyms 1,3-Dichloro-2-(methoxymethoxy)propane-1,1,2,3,3-d5; Bis(chloromethyl) Methylal-d5; 1,3-Dichloro-2-(MOM)propane-d5; Chloromethyl MOM Ether-d5 (dimer form); Deuterated DCMOM; [D5]-1,3-Dichloro-2-methoxymethoxypropane; MOM-protected bis(chloromethane)-d5
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Quality Control

Our deuterated chemicals are produced and controlled under a strict quality management system. Each batch of 1,3-Dichloro-2-(Methoxymethoxy)Propane-D5 is analyzed to confirm its chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) are provided, detailing results from NMR (¹H, ¹³C), mass spectrometry, and chromatographic assays. We support research requiring high isotopic enrichment and lot-to-lot consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity. Recommended long-term storage at 2-8°C.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (NMR) Conforms to structure
Isotopic Purity (D-enrichment) ≥ 98 atom % D
Chemical Purity (GC/HPLC) ≥ 95%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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