Description

Molindone-D8 is a deuterated analog of the antipsychotic agent molindone, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic toxicology, and clinical diagnostics sectors who require precise and reproducible data.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the analysis of molindone and its metabolites.
• Pharmacokinetic Research: Used in drug metabolism and pharmacokinetic (DMPK) studies to track drug absorption, distribution, metabolism, and excretion with high precision.
• Forensic Toxicology: Enables accurate quantification of molindone in biological matrices for forensic and clinical toxicology reports.
• Biomedical Research: Supports investigative studies on the mechanism of action and metabolic pathways of antipsychotic drugs.
• Pharmaceutical Quality Control: Employed in the development and validation of analytical methods for drug substance and product testing.
• Reference Material: Serves as a certified reference material (CRM) for calibrating analytical instruments and ensuring method compliance.

Basic Information

Product Name	Molindone-D8
CAS No.	1189805-13-7
Molecular Formula	C16H16D8N2O2
Molecular Weight	284.40 g/mol
Synonyms	3-Ethyl-1,5,6,7-tetrahydro-2-methyl-4H-indol-4-one-d8; 3-Ethyl-6,7-dihydro-2-methyl-5H-indol-4(1H)-one-d8; Molindone (hexadeutero); Molindone-d8; Deuterated Molindone; Molindone Internal Standard; [2H8]-Molindone
EINECS	Contact for details

Quality Control

Every batch of Molindone-D8 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical testing including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA), providing batch-specific data on purity, isotopic enrichment, and solvent residues, is supplied with each product to ensure compliance with research and regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.