Description

Butriptyline-D6 is a deuterated analog of the tricyclic antidepressant butriptyline, specifically labeled with six deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is a critical tool for researchers and quality control laboratories in the pharmaceutical and forensic toxicology sectors, where precise measurement of butriptyline and its metabolites is required.

Application

• Primary use as an Internal Standard for the quantification of butriptyline in LC-MS/MS and GC-MS bioanalytical methods.
• Pharmacokinetic and metabolic stability studies in pharmaceutical research and development.
• Forensic and clinical toxicology analysis for accurate drug level determination.
• Method development and validation in compliance with regulatory guidelines (e.g., FDA, EMA).
• Quality control and assurance testing in pharmaceutical manufacturing.
• Use in research investigating the drug metabolism and disposition (DMPK) of tricyclic antidepressants.

Basic Information

Product Name	Butriptyline-D6
CAS No.	1189736-19-3
Molecular Formula	C21H20D6N
Molecular Weight	298.48 g/mol
Synonyms	Butriptyline-d6; 10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine-α,α,β,β,γ,γ-d6; Deuterated Butriptyline; Butriptyline (hexadeuterated); Butriptyline Internal Standard; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-d6; Evadyne-d6
EINECS	Contact for details

Quality Control

Every batch of Butriptyline-D6 is manufactured and analyzed under strict quality protocols to ensure exceptional isotopic purity and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.