Description

Methotrimeprazine D6 (Racemic) CAS NO 1189734-21-1 is a deuterated, isotopically labeled analog of the phenothiazine derivative methotrimeprazine. This high-purity compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical workflows. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and forensic toxicology units for drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and clinical research.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a critical internal standard for the precise quantification of methotrimeprazine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Forensic and Clinical Toxicology: Used in method development and routine analysis for the confirmatory identification and quantification of methotrimeprazine in forensic casework and clinical overdose scenarios.
• Pharmaceutical Research & Development: Supports bioanalytical method validation, stability testing, and impurity profiling during drug development processes.
• Reference Standard for Isotope Dilution Analysis: Provides a stable, non-radioactive isotopic label to correct for analyte loss during sample preparation and instrument variability.

Basic Information

Product Name	Methotrimeprazine D6 (Racemic)
CAS No.	1189734-21-1
Molecular Formula	C19H16D6N2S
Molecular Weight	312.49 g/mol
Synonyms	Levomepromazine D6 (Racemic); Methotrimeprazine-d6; 2-Methoxy-10-[2-(1-methyl-2-piperidyl)ethyl]phenothiazine-d6; (±)-Levomepromazine-d6; 3-(2-Methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine-d6; Deuterated Methotrimeprazine; Methotrimeprazine Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Methotrimeprazine D6 (Racemic) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic techniques, to ensure compliance with the high-purity standards required for analytical applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.