Description

Di--Carbethoxyethyl-D8-Methylamine CAS NO 1189723-57-6 is a high-purity, deuterium-labeled amine derivative, serving as a critical stable isotope-labeled intermediate. Its primary value lies in enabling advanced analytical and research applications where precise molecular tracking and quantification are essential. This compound is particularly vital for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require labeled standards for mass spectrometry, metabolic studies, and the development of novel active ingredients.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of its non-deuterated analogs or related metabolites.
• Pharmaceutical Research & Development: Employed as a labeled building block in the synthesis of deuterated drug candidates for pharmacokinetic (PK), pharmacodynamic (PD), and absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolic Pathway Tracing: Facilitates the study of biochemical pathways and metabolic fate in biological systems due to its stable isotopic label.
• Agrochemical Research: Acts as a key intermediate in developing labeled pesticides or herbicides for environmental fate and residue analysis studies.
• Analytical Reference Material: Serves as a high-purity certified reference material (CRM) for calibrating analytical instruments and validating methods.
• Chemical Synthesis Intermediate: Utilized in organic synthesis to introduce a deuterated amine functional group into more complex molecular architectures.

Basic Information

Product Name	Di--Carbethoxyethyl-D8-Methylamine
CAS No.	1189723-57-6
Molecular Formula	C11D8H11NO4 (or related based on structure)
Molecular Weight	Contact for details
Synonyms	Bis(2-ethoxy-2-oxoethyl)-D8-methylamine; Diethyl (D8-methylamino)malonate; D8-Methyliminodiacetic acid diethyl ester; Deuterated Methyliminodiacetic Acid Diethyl Ester; N-(D8-Methyl)iminodiacetic Acid Diethyl Ester; 2,2'-((D8-Methyl)azanediyl)diacetic acid diethyl ester; D8-N-Methyliminodiacetic Acid Diethyl Ester; Labeled NMDA Diethyl Ester
EINECS	Contact for details

Quality Control

Our Di--Carbethoxyethyl-D8-Methylamine is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analysis, including NMR (¹H, ¹³C) for structural confirmation, HPLC/GC for chemical purity, and Mass Spectrometry to verify isotopic enrichment (D8 label). A detailed Certificate of Analysis (COA) specifying purity, isotopic purity, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D8)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.