Description

1,1,2,2-Tetradeuterio-2-(4-Fluorophenyl)Ethanol is a deuterium-labeled analog of 2-(4-Fluorophenyl)ethanol, a key intermediate and building block in organic synthesis. This compound is specifically designed for use as an internal standard in mass spectrometry and for tracing metabolic pathways in pharmacokinetic and drug metabolism studies. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries who require high-purity, isotopically labeled materials for advanced R&D and quality control.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the precise quantification of its non-deuterated counterpart in complex biological matrices.
• Metabolic Pathway Tracing: Used in drug discovery and development to study the absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical candidates.
• Pharmaceutical Intermediate: Acts as a deuterated building block for the synthesis of more complex, isotopically labeled active pharmaceutical ingredients (APIs) and probes.
• Analytical Reference Standard: Provides a certified material for calibrating analytical instruments and validating methods in quality control laboratories.
• Mechanistic Studies: Enables detailed investigation of reaction mechanisms and enzymatic processes where hydrogen/deuterium exchange is relevant.

Basic Information

Product Name	1,1,2,2-Tetradeuterio-2-(4-Fluorophenyl)Ethanol
CAS No.	1189710-73-3
Molecular Formula	C8H4D4FO
Molecular Weight	142.18 g/mol
Synonyms	2-(4-Fluorophenyl)ethanol-d4; 4-Fluorophenethyl-d4 alcohol; [2H4]-2-(4-Fluorophenyl)ethan-1-ol; 1,1,2,2-Tetradeuterio-2-(p-fluorophenyl)ethanol; Deutero-p-fluorophenethyl alcohol; (4-Fluorophenyl)-1,1,2,2-d4-ethanol; p-Fluorophenethyl-d4 alcohol
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality management to ensure the highest isotopic and chemical purity for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (D atom %), chemical purity, and identity confirmation. We support compliance with cGMP and ISO 9001 standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0% (by MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.