Description

3-[2-[[3-(9H-Carbazol-4-Yloxy)-1,1,2,3,3-Pentadeuterio-2-Hydroxypropyl]Amino]Ethoxy]-4-Methoxyphenol is a deuterated derivative of a carbazole-based phenolic compound, offering enhanced metabolic stability and traceability for advanced research applications. This high-value specialty chemical is critical for pharmaceutical development, particularly in the creation of deuterated drug candidates where improved pharmacokinetic profiles are desired. It serves as a key intermediate for researchers and manufacturers in medicinal chemistry, isotope labeling, and analytical standard development.

Application

• Pharmaceutical Intermediate: Acts as a crucial building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular pathways.
• Isotope Labeling Reagent: Used in the preparation of stable isotope-labeled compounds for mass spectrometry-based bioanalytical studies and pharmacokinetic research.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a deuterated analog to probe metabolic soft spots and improve drug-like properties.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in regulatory submissions.
• Biochemical Probe Development: Utilized in the design of molecular probes for studying enzyme mechanisms and receptor interactions where deuterium substitution is beneficial.
• Advanced Material Synthesis: Potential precursor for specialized organic electronic materials due to the carbazole moiety's charge-transport properties.

Basic Information

Item	Detail
Product Name	3-[2-[[3-(9H-Carbazol-4-Yloxy)-1,1,2,3,3-Pentadeuterio-2-Hydroxypropyl]Amino]Ethoxy]-4-Methoxyphenol
CAS No.	1189704-21-9
Molecular Formula	C24H23D5N2O4
Molecular Weight	~419.52 g/mol
Synonyms	4-Methoxy-3-[2-[[3-(9H-carbazol-4-yloxy)-1,1,2,3,3-pentadeuterio-2-hydroxypropyl]amino]ethoxy]phenol; Deuterated Carvedilol Metabolite Intermediate; 3-(2-((3-(9H-Carbazol-4-yloxy)-1,1,2,3,3-pentadeuterio-2-hydroxypropyl)amino)ethoxy)-4-methoxyphenol; 4-Hydroxy-3-methoxyphenoxyethylamino-propaned5-ol Carbazole Ether; [D5]-3-(9H-Carbazol-4-yloxy)-1,1,2,3,3-pentadeuterio-2-[(2-hydroxy-4-methoxyphenoxy)ethylamino]propan-1-ol
EINECS	Contact for details

Quality Control

Our production of 3-[2-[[3-(9H-Carbazol-4-Yloxy)-1,1,2,3,3-Pentadeuterio-2-Hydroxypropyl]Amino]Ethoxy]-4-Methoxyphenol adheres to stringent quality management systems. Each batch is characterized and released based on comprehensive analytical data including NMR (¹H, ¹³C, and ²H), HPLC, and mass spectrometry to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (²H NMR/MS)	≥ 95 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.